U.S. Venture Partners

U.S. Venture Partners (USVP) is a distinguished venture capital firm headquartered in Menlo Park, California, deeply embedded in the heart of Silicon Valley’s innovation ecosystem. Established in 1981, USVP has forged a powerful legacy of aiding entrepreneurs in transforming visionary ideas into industry-leading companies. With a primary focus on early-stage start-ups, the firm specializes in several key industry segments including enterprise software, cyber security, consumer, e-commerce, healthcare, and IT-enabled healthcare services.

Throughout its four-decade-long history, USVP has invested $4.4 billion in 526 companies. Impressively, 93 of these companies have gone public, a testament to USVP’s skill in identifying and nurturing market leaders. Some of the firm’s most impactful investments include notable companies such as Arkose Labs, Box, Carrot Fertility, Cato Networks, Check Point Software, Guidewire, Happy Returns, HeartFlow, HotelTonight, Human Interest, Imperva, Inari Medical, Inspire Medical Systems, Intersect ENT, Kenna, Medigate, Omada Health, Pluto TV, Standard Bariatrics, ThreatMetrix, Trunk Club, Trusteer, Yammer, and Zerto.

Currently driving innovation and supporting entrepreneurs from its thirteenth fund, USVP XIII, the firm maintains a steadfast commitment to successful venture investing. The experienced team at USVP comprises former entrepreneurs, technologists, corporate executives, and financial professionals, all of whom bring invaluable expertise. This team plays a vital role in assisting portfolio companies with strategy formulation, scaling operations, team building, product development, and business development, ensuring these companies are equipped to achieve success.

Noteworthy accomplishments from USVP’s recent investments include significant funding rounds and advancements in personalized healthcare and financial technology. For instance, in 2024, Carlsmed raised $52.5 million in Series C financing to advance personalized spine surgery, highlighting USVP’s focus on transformative healthcare solutions. Similarly, the retirement startup Human Interest was valued at $1.33 billion in a new $267 million financing round, underscoring USVP's impact in the fintech space.

Through its extensive network of over 500 companies and 5,000 executives, USVP leverages a multigenerational knowledge base and broad industry experience. This connectivity and expertise allow USVP to provide unmatched support to its portfolio companies, ensuring these start-ups not only thrive but also lead their respective markets.

For more information, visit USVP’s website at https://www.usvp.com/.

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