San Francisco's status as a global epicenter for technology and innovation attracts top-tier venture capital firms from around the world. These top 10 venture capital firms in San Francisco actively seek out and invest in the brightest startups, fueling the city's entrepreneurial spirit and driving advancements in technology and business.
Through their investments and support, these firms play a vital role in shaping the future of the dynamic and ever-evolving landscape of San Francisco's startup ecosystem.
The competition, of course, is even more fierce and fast than almost anywhere else in the world. The best way to be certain that your pitch deck will resonate and hit the jackpot with a VC firm and other investors, is by getting our team of expert pitch deck writers and designers on your side.
UpHonest Capital, based in San Francisco, CA, invests in early-stage tech-driven startups across AI, IoT, cloud computing, and big data, with a portfolio of 466 companies including 28 unicorns. Focus industries span mobile internet, biotech, fintech, and more. Their ecosystem programs and media contributions foster global innovation and entrepreneurship.
Union Square Ventures is a prominent New York-based venture capital firm known for its focus on disruptive technology companies. Their diverse portfolio includes investments in cryptocurrency, fintech, and other cutting-edge industries, making them a key player in the city's dynamic tech scene.
Greycroft, a premier VC firm with offices in NYC and LA, invests in fintech, e-commerce, media, health, and consumer brands, specifically in AI, sustainability, and software solutions. Managing over $1B in assets with a portfolio of 150+ companies, it supports entrepreneurs via robust media and tech networks. Notable investments include Acorns, Venmo, and TheRealReal.
‍ As one of the most influential venture capital firms in the world, Benchmark is deeply rooted in the San Francisco startup community. They are known for their early-stage investments and hands-on support to help startups scale and thrive.
Sequoia Capital, based in Menlo Park, California, is a renowned venture capital firm with over 50 years of experience, investing in technology, AI, healthcare, and security. Known for nurturing iconic companies from Apple to Zoom, Sequoia’s investments benefit non-profits and educational institutions, highlighting their unwavering commitment to innovation and societal impact.
With a global presence, Accel Partners also maintains a significant focus on San Francisco. Their portfolio includes companies across various sectors, and they are committed to nurturing entrepreneurship and driving innovation in the region.
Kleiner Perkins, a pioneering venture fund located in Silicon Valley, invests $10 billion in technology and life sciences, supporting companies from early-stage startups to growth-stage leaders like Amazon, Google, Spotify, and UiPath, across industries including AI, mental health, biotech, energy, and sustainable food supplies, fostering transformative innovations.
Andreessen Horowitz (a16z) is a venture capital firm based in Silicon Valley, established in 2009 by Marc Andreessen and Ben Horowitz, investing stage-agnostic in consumer, enterprise, bio/healthcare, crypto, fintech, and games industries, advocating for startups, regulatory reforms, and American technology supremacy.
First Round Capital, based in San Francisco with offices in NYC and Philadelphia, invests $1M-$5M primarily in U.S. early-stage tech startups across enterprise software, fintech, consumer technologies, and healthcare. They provide hands-on operational guidance, a strong mentorship network, and support in hiring and growth, focusing on founders' resilience and innovation.
Founders Fund, based in San Francisco, is a premier venture capital firm known for investing in transformative ventures across all stages and sectors worldwide, supporting innovative companies like PayPal, SpaceX, and Airbnb with capital, expertise, and strategic guidance to drive significant industry impact and foster groundbreaking solutions.